List_of_Extremely_Hazardous_Substances

La pipéridine se retrouve dans la liste précédente. C'est une substance extrêmement dangereuse.

Tous ces antipsychotiques/neuroleptiques sont fait à partir de pipéridine : Haldol, Risperdal, Thioridazine (Mellaril, Mallorol, Novorizadine, and Thioril), Droperidol (Dropletan, Dridol or Inapsine), Mesoridazine (Serentil), Melperone (Buronil, Burnil, Eunerpan).

Le PCP, la pire cochonnerie de drogue que tu peux trouver sur la rue (souvent vendu comme de la mescaline, même si ce n'en est pas) est aussi fait à partir de pipéridine.

La pipéridine est utilisée pour produire le ditran: une arme chimique.

http://msds.chem.ox.ac.uk/PI/piperidine.html
Toxicology:
"Poison. May be fatal if inhaled or swallowed. Severe irritant. Skin contact may cause severe irritation or burns. Contact with the eyes may lead to permanent damage."

Voici un extrait de l'article wikipedia sur la pipéridine suivi d'extraits d'articles sur les 2 substances cités en dernier dans le paragraphe suivant.

"Otherwise piperidine and its derivatives are ubiquitous building blocks in the synthesis of pharmaceuticals and fine chemicals. The piperidine structure is e.g. found in the pharmaceuticals risperidone, raloxifene, minoxidil, thioridazine, haloperidol, droperidol, mesoridazine, meperidine, melperone the psychochemical agents Ditran-B (JB-329), N-methyl-3-piperidyl benzilate (JB-336) and in many others."

"Piperidine is listed as a Table II precursor under the United Nations Convention Against Illicit Traffic in Narcotic Drugs and Psychotropic Substances due to its use (peaking in the 1970s) in the clandestine manufacture of PCP (also known as angel dust)."

//////

"N-methyl-3-piperidyl benzilate (JB-336) is an anticholinergic drug related to the chemical warfare agent 3-Quinuclidinyl benzilate. N-methyl-3-piperidyl benzilate is less potent and shorter acting than 3-quinuclidyl benzilate, but like 3-QNB its effects on the central nervous system predominate over peripheral effects. It produces deliriant and hallucinogenic effects similar to those of plants such as datura and may be used recreationally at low doses, however unpleasant side effects such as dysphoria, nausea and vomiting, dizziness and extreme dry mouth tend to make abuse of these kind of drugs uncommon. Both the N-methyl and N-ethyl analogues of 3-piperidyl benzilate are however Schedule I controlled drugs."

//////

"Ditran was developed during chemical weapons research in an attempt to produce non-lethal incapacitating agents, similar to QNB itself. The ditran mixture is more potent as an anticholinergic than the piperidyl benzilate drugs such as N- methyl- 3 -piperidyl benzilate, but is less potent than QNB."